منابع مشابه
Hyposplenism in gastrointestinal disease.
The hazards of living without a spleen were recognised by the paediatricians in the early 1960's when they focussed attention on the syndrome of fulminant sepsis, often due to pneumococcal infection, occurring in young children within the fIrst two years of splenectomy 1. A child, well at breakfast, might be febrile by lunch, comatose by evening and dead by the following morning. We now recogni...
متن کاملFunctional hyposplenism following allogeneic bone marrow transplantation.
AIMS To investigate the incidence of functional hyposplenism in a group of patients who had undergone allogeneic bone marrow transplantation (BMT). METHODS Splenic function was assessed by counting the number of gluteraldehyde fixed red blood cells containing pits or indentations as examined by interference phase microscopy. Normal values are < 2% whereas splenectomy patients have values of 2...
متن کاملPrimary pulmonary hypertension and functional hyposplenism.
Primary pulmonary hypertension is a rare disease of unknown case. Functional hyposplenism is characterized by the appearance of abnormal circulating erythrocytes despite the presence of a spleen and is associated with a variety of disease states. A case of primary pulmonary hypertension associated with functional hyposplenism is described in this report.
متن کاملClinical picture Grave’s disease and acquired hyposplenism
A 38-year-old Caucasian woman was referred to the hematology clinic for unexplained leukocytosis and thrombocytosis and ‘possible myeloproliferative disorder’. Her history included only Grave’s disease (GD) in remission for 2 years after methimazole treatment. A recent blood count revealed hemoglobin content to be 12.8 g/dl; white blood cells 20.7 10 m/l (neutrophils 9.5 10; lymphocytes 8.3 10;...
متن کاملPlatelet hyperactivity in sickle-cell disease: a consequence of hyposplenism.
Platelet function was measured on 29 occasions in 16 adult patients in the asymptomatic steady state of sickle-cell anaemia. There was a significant increase in platelet number and micro-aggregate formation, and a lower aggregation threshold with adenosine diphosphate, compared with 23 healthy controls. Similar changes were found, however, in 12 splenectomised patients without sickle-cell disea...
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ژورنال
عنوان ژورنال: Canadian Medical Association Journal
سال: 2019
ISSN: 0820-3946,1488-2329
DOI: 10.1503/cmaj.70852